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KMID : 0359920070260020264
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Korean Journal of Nephrology
2007 Volume.26 No. 2 p.264 ~ p.268
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A Case of Unilateral Renal Artery Stenosis with Contra-Lateral Focal Segmental Glomerulosclerosis in a Chronic Kidney Disease Patient
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Hong Sung-Jin
Kim Dong-Kie
Ku Cheol-Ryong
Lee Han-Sung
Choi Kyu-Hun
Lee Ho-Yung
Han Dae-Suk
Jeong Hyeon-Joo
Kim Beom-Seok
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Abstract
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We report a case of focal segmental glomerulosclerosis (FSGS) with chronic renal failure in a patient with unilateral renal artery stenosis. A 38-year-old woman presented with malignant hypertension, massive proteinuria and renal insufficiency. MR angiography showed proximal stenosis of the right renal artery and biopsy of the left kidney revealed focal segmental glomerulosclerosis. The patient responded favorably to the angiotensin II receptor antagonist, as the blood pressure and urinary protein decreased. This case showed that FSGS is a pathophysiologic mechanism of renal injury in uncontrolled renovascular hypertension.
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KEYWORD
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Focal glomerulosclerosis, Malignant hypertension, Renal insufficiency, Renal artery obstruction
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